The problem with applying vacuum to a HHO cell is that it lowers the boiling point of the electrolyte. We do not want it to boil. I added a valve between the bubbler and vacuum port on my intake to limit the vacuum to the system. I also vented the cell with a small tube that allows air to bubble up from the bottom of the cell. The vent has a one way check valve installed to prevent any water from syphoning out. I adjust the vacuum to the bubbler using the valve until I notice air being drawn into the vent and then back it off a bit. This needs only to be done at idle because that is when the vacuum is highest. I also tee off the output of the bubbler and run a hose to the intake just in front of the throttle body. Another one way check valve prevents air being sucked into the vacuum port at idle and allows HHO gas to flow into the intake when engine is operating at highway speeds and no vacuum is present.